E1105 / Other additives
Lysozyme
Safety in brief
Safe
Recorded EatMatrix rating, not a new clinical review. The amount, your sensitivities and country rules still matter.
- Watch for
- Recorded allergens: egg.
- Our advice
- Read the whole food label and consider how often you eat the product. A name or E number does not tell you the amount, and an ingredient rating cannot assess the entire food.
What it is
Lysozyme is an enzyme naturally found in egg whites, tears, and saliva that has antimicrobial properties, breaking down certain bacterial cell walls. It is used mainly in cheesemaking (especially hard cheeses like some Parmesan-style products) to prevent late blowing caused by Clostridium bacteria. Because it is derived from egg, lysozyme is a known allergen for people with egg allergies.
Also appears on labels as: Lysozyme, E1105, E 1105, E-1105, Egg white lysozyme, Hen egg-white lysozyme, HEWL, Muramidase, N-acetylmuramide glycanhydrolase, Lysozyme enzyme, Lysozyme powder, Lysozyme additive.
Dietary information
- Vegan
- No
- Halal
- Yes
- Gluten-free
- Yes
- Allergens
- egg
Recorded ingredient information. Check the product label or certification: sources, other ingredients and cross-contact can vary.
Research & body effects
Health notes from our ingredient record
- Derived from egg white; poses a risk for people with egg allergy.
- Generally recognized as safe for non-allergic individuals at the levels used in cheesemaking.
Other references from our ingredient record
These links come from the original ingredient record. They are separate from the source reviews above and have not all been checked for the exact ingredient, amount consumed or claim. Dates are shown newest first.
- Lysozyme (E1105) – Safety Review — EFSA Panel on Food Additives, EFSA Journal (2014). Enzyme derived from egg white; EFSA ADI not specified; safe; allergenic potential for egg-sensitive individuals.[safe_in_moderation]
Country rules
Country checks for E1105
Permission depends on the market, type of food, amount and conditions. A scientific opinion or an E-number alone does not establish a legal use. These checks are separate from the stored EatMatrix rating.
Compare all eight markets and their sources
| Market | What is checked |
|---|---|
| European Union | Regulation (EC) 1333/2008, Annex II Part B, version , contains the exact code E1105: Lysozyme. Listing alone does not allow every food use. Part E food categories, limits, specifications and applicable later acts still need a product-specific check. Source read: . |
| Great Britain | The FSA register record for E1105 (Lysozyme) lists “Authorised” in England, Scotland and Wales. Register updated: 01 April 2025; record checked: . Food-specific conditions and specifications still need a separate legal check. |
| United States | Complete current-use review pending. Any scoped provision in the label guide above applies only to the stated use. FDA explains the applicable food-additive and GRAS framework. |
| Northern Ireland | Review pending. Check the applicable EU rules and territory arrangements; the GB register alone does not establish this status. FSA guidance is a starting source, not a verified permission for this entry. |
| Canada | Named food-use records located. Health Canada lists the preparations below for specified foods and purposes. This is conditional permission for those uses, not approval of every product or a personal safety verdict. The enzyme name alone does not identify the permitted source organism or production strain. Each source and food-use condition below must also match. Source tables captured . List publication dates are shown separately. Good Manufacturing Practice (GMP) is a condition of use, not an unlimited amount or a recommended intake. Food and Drug Regulations B.16.003 requires the listed source, purpose, amount and other conditions to match. The official consolidation read was current to 21 September 2026; product specifications and applicable later changes still need checking. Read 1 listed food-use conditionsLysozymeHealth Canada: List of Permitted Food Enzymes. List published ; item L.6.
EatMatrix reading: match the exact preparation and food first. A manufacturing limit is not an acceptable daily intake (ADI). A label without the amount cannot establish exposure, and an unlisted name here does not establish a ban. |
| Australia | Review pending. Food Standards Code permissions and conditions need an additive-specific check. FSANZ food-additive rules is a starting source, not a verified permission for this entry. |
| New Zealand | Review pending. Food Standards Code permissions and conditions need an additive-specific check. FSANZ food-additive rules is a starting source, not a verified permission for this entry. |
| Japan | Review pending. The relevant list, identity and use standards need an additive-specific check. CAA food-additive lists is a starting source, not a verified permission for this entry. |
Sources & review status
Check what each source covers: an authority’s conclusion, a research finding and a country’s legal permission answer different questions.
What this guide covers
- Original ingredient record
- 1 research link; newest recorded date: . Sources added separately to this guide are not included in this count.
This guide brings together our ingredient record and the dated sources shown here. Missing information describes a gap in this guide; it does not mean an ingredient is untested, safe or harmful. This is not a complete review of every study, preparation or current country rule. The amount in a product and how it is used still matter.
How to read the ratings, research and country checksAgency labels recorded by EatMatrix
These are imported database classifications, not verified current statements from each authority. Use the dated official sources below for their actual scope and conclusions.
| Authority | Database label |
|---|---|
| FDA | Safe |
| WHO | Safe |
| EFSA | Safe |
| FSANZ | Safe |
| Japan | Safe |
| UK FSA | Safe |
| Health Canada | Safe |
Database updated: . What does an E number mean on a food label?
Common questions
Frequently asked questions
What is EatMatrix's recorded rating for E1105?
The recorded EatMatrix rating for E1105 (Lysozyme) is “Safe”. It is calculated from labels stored in our ingredient database. These labels are not verified current regulator decisions or country permissions. A database update date is not a scientific review date.
Is E1105 vegan, halal or gluten-free?
According to our ingredient data for Lysozyme — vegan: no, vegetarian: yes, halal: yes, kosher: yes, gluten-free: yes, dairy-free: no. Manufacturing sources can vary between products; check the label if it matters to you.
What is E1105 and why is it used?
Lysozyme is an enzyme naturally found in egg whites, tears, and saliva that has antimicrobial properties, breaking down certain bacterial cell walls. It is used mainly in cheesemaking (especially hard cheeses like some Parmesan-style products) to prevent late blowing caused by Clostridium bacteria. Because it is derived from egg, lysozyme is a known allergen for people with egg allergies.
Does E1105 contain allergens?
Yes — known allergens associated with Lysozyme: egg.
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This page shows information and classifications recorded in our ingredient database. Current scientific and market-specific verification remains pending as described above. It is general information, not medical advice.