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E280 / Preservatives

Propionic acid

Selected sources checked · Scope & sources

Safety in brief

Safe

Recorded EatMatrix rating, not a new clinical review. The amount, your sensitivities and country rules still matter.

Watch for
No allergen or sensitivity is recorded for this ingredient here. Check the whole product label; this is not an allergen-free guarantee.
Our advice
Read the whole food label and consider how often you eat the product. A name or E number does not tell you the amount, and an ingredient rating cannot assess the entire food.
What it is

Propionic acid is a naturally occurring acid also produced by fermentation, used as a preservative to stop mold and some bacteria from growing in bread, baked goods, and cheese. It is present naturally in small amounts in dairy products like Swiss cheese. Regulatory bodies including the FDA and EFSA consider it safe at the levels used in food.

Also appears on labels as: Propionic acid, CH3CH2COOH, C3H6O2, E280, E 280, E-280, INS 280, Propanoic acid, Methylacetic acid, Ethylformic acid, Carboxyethane, Propan-1-oic acid.

Dietary information

Vegan
Yes
Halal
Yes
Gluten-free
Yes
Allergens
None recorded

Recorded ingredient information. Check the product label or certification: sources, other ingredients and cross-contact can vary.

Research & body effects

Health notes from our ingredient record

  • Some early animal studies raised questions about behavioral effects at high doses, but this is not confirmed as a concern at normal dietary exposure.
  • Rarely associated with migraine triggers or mild digestive upset in sensitive individuals.

Other references from our ingredient record

These links come from the original ingredient record. They are separate from the source reviews above and have not all been checked for the exact ingredient, amount consumed or claim. Dates are shown newest first.

  1. Scientific Opinion on the re-evaluation of propionic acid (E 280), sodium propionate (E 281), calcium propionate (E 282) and potassium propionate (E 283) as food additives — EFSA Panel on Food Additives, EFSA Journal (2014). Official EFSA scientific opinion (bibliographic reference, imported 2026-10-13). It covers the additive as a group assessment and is not an individual human study; read the opinion for its findings.
Country rules

Country checks for E280

Permission depends on the market, type of food, amount and conditions. A scientific opinion or an E-number alone does not establish a legal use. These checks are separate from the stored EatMatrix rating.

Compare all eight markets and their sources
MarketWhat is checked
European Union

Regulation (EC) 1333/2008, Annex II Part B, version , contains the exact code E280: Propionic acid.

Listing alone does not allow every food use. Part E food categories, limits, specifications and applicable later acts still need a product-specific check. Source read: .

Great Britain

The FSA register record for E280 (Propionic acid) lists “Authorised” in England, Scotland and Wales.

Register updated: 01 April 2025; record checked: . Food-specific conditions and specifications still need a separate legal check.

United States

Selected US conditions for Propionic acid

Official federal text current through ; read .

Food uses, limits and exceptions

Named antimicrobial and flavouring uses

The specified preparation is affirmed GRAS for the listed antimicrobial and flavouring uses under current good manufacturing practice. This is an identity- and use-specific provision; it does not transfer automatically to every propionate salt.

21 CFR 184.1081 · 21 CFR 184.1

EatMatrix’s reading: a legal use condition answers where and how an ingredient may be used. It is not a test of your product, a personal safe intake or a claim that the ingredient benefits your body. Match the named substance, food and amount. Other federal provisions, food standards, state rules and later changes may also apply; this is a selected source review, not a complete product-compliance decision.

Northern Ireland

Review pending. Check the applicable EU rules and territory arrangements; the GB register alone does not establish this status. FSA guidance is a starting source, not a verified permission for this entry.

Canada

Named food-use records located. Health Canada lists the preparations below for specified foods and purposes. This is conditional permission for those uses, not approval of every product or a personal safety verdict.

Only the named records and conditions below were located. Exact composition and specifications still need matching.

Source tables captured . List publication dates are shown separately. Good Manufacturing Practice (GMP) is a condition of use, not an unlimited amount or a recommended intake.

Food and Drug Regulations B.16.003 requires the listed source, purpose, amount and other conditions to match. The official consolidation read was current to 21 September 2026; product specifications and applicable later changes still need checking.

Read 4 listed food-use conditions

Propionic Acid

Health Canada: List of Permitted Preservatives. List published ; item P.10.

  • Food: (a) Bread

    Purpose: (a) Preservative

    Limit and conditions: (a) If used singly, the amount not to exceed 2,000 ppm. If used in combination with calcium propionate or sodium propionate, or both, the total combined amount not to exceed 2,000 ppm, calculated as propionic acid.

  • Food: (b) Cheddar cheese; (Naming the variety) cheese; Cold-pack cheese food; Cold-pack cheese food with (naming the added ingredients); Cold-pack (naming the variety) cheese; Cold-pack (naming the variety) cheese with (naming the added ingredients); Cream cheese; Cream cheese with (naming the added ingredients); Cream cheese spread; Cream cheese spread with (naming the added ingredients); Processed (naming the variety) cheese; Processed cheese food; Processed cheese food with (naming the added ingredients); Processed cheese spread; Processed cheese spread with (naming the added ingredients); Processed (naming the variety) cheese with (naming the added ingredients)

    Purpose: (b) Preservative

    Limit and conditions: (b) If used singly, the amount not to exceed 2,000 ppm. If used in combination with calcium propionate or sodium propionate, or both, the total combined amount not to exceed 2,000 ppm, calculated as propionic acid. If used in any combination with calcium propionate, sodium propionate, calcium sorbate, potassium sorbate, sodium sorbate or sorbic acid, the total combined amount not to exceed 3,000 ppm, calculated as propionic acid and sorbic acid, respectively, provided that the amount of propionic acid does not exceed 2,000 ppm.

  • Food: (c) Ready-to-eat prepared meat or ready-to-eat prepared meat by-product; Ready-to-eat prepared poultry meat or ready-to-eat prepared poultry meat by-product; Ready-to-eat preserved meat or ready-to-eat preserved meat by-product; Ready-to-eat preserved poultry meat or ready-to-eat preserved poultry meat by-product; Wiener

    Purpose: (c) Preservative

    Limit and conditions: (c) If used singly, the amount not to exceed 2,500 ppm. If used in combination with sodium propionate, the total combined amount not to exceed 2,500 ppm, calculated as propionic acid.

    Source modification reference: NOM/ADM-0112 (see the official list).

  • Food: (d) Unstandardized foods, except unstandardized preparations of meat or meat by-product, fish or meat (as defined in section B.21.002 of the Food and Drug Regulations ) or poultry meat or poultry meat by-product

    Purpose: (d) Preservative

    Limit and conditions: (d) If used singly, the amount not to exceed 2,000 ppm. If used in combination with calcium propionate or sodium propionate, or both, the total combined amount not to exceed 2,000 ppm, calculated as propionic acid.

    Source modification reference: NOM/ADM-0122 (see the official list).

EatMatrix reading: match the exact preparation and food first. A manufacturing limit is not an acceptable daily intake (ADI). A label without the amount cannot establish exposure, and an unlisted name here does not establish a ban.

Australia

Review pending. Food Standards Code permissions and conditions need an additive-specific check. FSANZ food-additive rules is a starting source, not a verified permission for this entry.

New Zealand

Review pending. Food Standards Code permissions and conditions need an additive-specific check. FSANZ food-additive rules is a starting source, not a verified permission for this entry.

Japan

Review pending. The relevant list, identity and use standards need an additive-specific check. CAA food-additive lists is a starting source, not a verified permission for this entry.

Sources & review status

Check what each source covers: an authority’s conclusion, a research finding and a country’s legal permission answer different questions.

What this guide covers

Official assessment sources
Commission-listed EFSA references for E280. Bibliographic identity checked; latest findings and current use rules need separate review.
Original ingredient record
1 research link; newest recorded date: . Sources added separately to this guide are not included in this count.

This guide brings together our ingredient record and the dated sources shown here. Missing information describes a gap in this guide; it does not mean an ingredient is untested, safe or harmful. This is not a complete review of every study, preparation or current country rule. The amount in a product and how it is used still matter.

How to read the ratings, research and country checks
Agency labels recorded by EatMatrix

These are imported database classifications, not verified current statements from each authority. Use the dated official sources below for their actual scope and conclusions.

AuthorityDatabase label
FDASafe
WHOSafe
EFSASafe
FSANZSafe
JapanSafe
UK FSASafe
Health CanadaSafe

Official assessment sources for E280

The European Commission’s re-evaluation table lists official EFSA documents for this additive. Their identifiers and subjects were checked against publisher bibliographic records. A missing research link in the EatMatrix database does not mean the additive has never been assessed.

Name in the Commission table: Propionic acid.

These are assessment references, including historical or group assessments. They do not establish the latest scientific conclusion, a human health benefit or risk, or current permission to use the additive in a particular food. Later assessments, corrections and food-use conditions need separate review. The recorded EatMatrix rating above is unchanged.

European Commission re-evaluation table, status as of . EatMatrix checked this bibliography on .

Database updated: . What does an E number mean on a food label?

Common questions

Frequently asked questions

What is EatMatrix's recorded rating for E280?

The recorded EatMatrix rating for E280 (Propionic acid) is “Safe”. It is calculated from labels stored in our ingredient database. These labels are not verified current regulator decisions or country permissions. A database update date is not a scientific review date.

Is E280 vegan, halal or gluten-free?

According to our ingredient data for Propionic acid — vegan: yes, vegetarian: yes, halal: yes, kosher: yes, gluten-free: yes, dairy-free: yes. Manufacturing sources can vary between products; check the label if it matters to you.

What is E280 and why is it used?

Propionic acid is a naturally occurring acid also produced by fermentation, used as a preservative to stop mold and some bacteria from growing in bread, baked goods, and cheese. It is present naturally in small amounts in dairy products like Swiss cheese. Regulatory bodies including the FDA and EFSA consider it safe at the levels used in food.

Does E280 contain allergens?

No known allergens are recorded for Propionic acid.

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This page shows information and classifications recorded in our ingredient database. Current scientific and market-specific verification remains pending as described above. It is general information, not medical advice.