E450 · Diphosphates
We haven’t recorded a regulator assessment for Diphosphates yet. The information below comes from our ingredient database; a verdict will appear here once EFSA, FDA or WHO positions are added.
What is E450?
Diphosphates are phosphate salts used in food mainly as raising agents, stabilizers, and sequestrants. They help baked goods rise, keep processed meats and seafood moist, and prevent discoloration in potatoes and seafood. They are common in instant puddings, cured meats, and canned seafood. While approved for food use, they contribute to overall dietary phosphate intake, which is a concern for people who need to limit phosphorus.
Also appears on labels as: E450, E 450, E-450, Diphosphates, Disodium diphosphate, Trisodium diphosphate, Tetrasodium diphosphate, Tetrapotassium diphosphate, Dicalcium diphosphate, Calcium diphosphate, Sodium diphosphates, Potassium diphosphates.
What the evidence says
- High total phosphate intake (from additives across many processed foods) is linked to cardiovascular and bone concerns, especially for people with impaired kidney function.
- People with chronic kidney disease are often advised to limit phosphate additives specifically.
- Generally recognized as safe for the general population at typical dietary levels.
Research behind the verdict
- Re‐evaluation of phosphoric acid–phosphates – di‐, tri‐ and polyphosphates (E 338–341, E 343, E 450–452) as food additives and the safety of proposed extension of use — EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), EFSA Journal (2019). The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion on phosphoric acid-phosphates including diphosphates (E 450) and polyphosphates (E 452). The Panel noted that phosphate intake from food additives may contribute significantly to total dietary phosphate exposure. The Panel recommended establishing group ADI values and emphasized the need to consider total dietary phosphate intake.[caution]
Frequently asked questions
Is E450 safe?
Our overall verdict for E450 (Diphosphates) is “Not yet rated”, based on the most cautious of the major regulators’ positions — no regulator assessment is recorded in our database yet.
Is E450 vegan, halal or gluten-free?
According to our ingredient data for Diphosphates — vegan: yes, vegetarian: yes, halal: yes, kosher: yes, gluten-free: yes, dairy-free: yes. Manufacturing sources can vary between products; check the label if it matters to you.
What is E450 and why is it used?
Diphosphates are phosphate salts used in food mainly as raising agents, stabilizers, and sequestrants. They help baked goods rise, keep processed meats and seafood moist, and prevent discoloration in potatoes and seafood. They are common in instant puddings, cured meats, and canned seafood. While approved for food use, they contribute to overall dietary phosphate intake, which is a concern for people who need to limit phosphorus.
Does E450 contain allergens?
No known allergens are recorded for Diphosphates.
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This page summarises publicly available regulatory assessments and research. It is general information, not medical advice. Sources: EFSA, FDA, WHO and the studies linked above.