E444 / Thickeners, stabilisers & emulsifiers
Sucrose acetate isobutyrate
Safety in brief
Safe
Recorded EatMatrix rating, not a new clinical review. The amount, your sensitivities and country rules still matter.
- Watch for
- No allergen or sensitivity is recorded for this ingredient here. Check the whole product label; this is not an allergen-free guarantee.
- Our advice
- Read the whole food label and consider how often you eat the product. A name or E number does not tell you the amount, and an ingredient rating cannot assess the entire food.
What it is
Sucrose acetate isobutyrate (SAIB) is a synthetic ester used mainly as a weighting agent in citrus-flavored soft drinks, keeping flavor oils evenly suspended so they don't float to the surface. It is also used as a glazing or coating agent in some confections. It is approved for food use within regulated limits by the FDA and EFSA.
Also appears on labels as: Sucrose acetate isobutyrate, SAIB, Sucrose acetic isobutyric ester, Sucrose ester of acetic and isobutyric acids, E444, E 444, E-444, Food emulsifier SAIB, Sucrose acetate-isobutyrate, Acetylated sucrose isobutyrate, Sucrose ester SAIB, Sacharozės acetatas izobutiratas.
What is E444 used for in food and drinks?
E444 is sucrose acetate isobutyrate, also called SAIB. A specified US food use is stabilising mixtures of flavouring oils in nonalcoholic beverages. In plain language, it helps keep those oil mixtures stable in a drink.
The relevant US rule is 21 CFR 172.833. It includes substance specifications and a maximum of 300 milligrams per kilogram of the finished beverage. This is a condition for that US beverage use, not an unrestricted permission for every food or country. E444 also differs from E445, which the FSA names glycerol esters of wood rosins.
- US eCFR 21 CFR 172.833: SAIB and beverage-use conditions
- WHO/JECFA: sucrose acetate isobutyrate, INS 444
- FSA additive names and E numbers (June 25, 2026)
See how EatMatrix reads an ingredient list before trying the app. Compare a scan with the physical label.
Identity and food-use sources checked . The E number alone does not tell you the amount in a product. Wider scientific and market checks are described below.
Dietary information
- Vegan
- Yes
- Halal
- Yes
- Gluten-free
- Yes
- Allergens
- None recorded
Recorded ingredient information. Check the product label or certification: sources, other ingredients and cross-contact can vary.
Research & body effects
Selected research on E444
How to read study types- Regulator reviewEFSA re-evaluation of sucrose acetate isobutyrate
Raised the safe daily limit to 20 mg per kg of body weight. No age group exceeds it, so no safety concern.
Summaries of each source's published abstract or statement, checked . This is a selection of sources, not a complete literature review. Authority assessments apply to the uses and places they cover.
Health notes from our ingredient record
- Generally recognized as safe at typical food-use levels used as a beverage weighting agent.
- High-dose animal studies have shown liver effects, but these greatly exceed realistic dietary exposure.
Other references from our ingredient record
These links come from the original ingredient record. They are separate from the source reviews above and have not all been checked for the exact ingredient, amount consumed or claim. Dates are shown newest first.
- Re‐evaluation of sucrose acetate isobutyrate (E 444) as a food additive — EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), EFSA Journal (2016). The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re-evaluating the safety of sucrose acetate isobutyrate (SAIB, E 444) as a food additive. The Panel agreed with the JECFA and SCF conclusions that the hepatic effects observed in the dog have little relevance to the safety evaluation in humans. The Panel concluded that there is no safety concern for the general population when SAIB (E 444) is used as a food additive.[safe]
- Re‐evaluation of sucrose acetate isobutyrate (E 444) as a food additive — EFSA Panel on Food Additives, EFSA Journal (2016). Official EFSA scientific opinion (bibliographic reference, imported 2026-10-13). It covers the additive as a group assessment and is not an individual human study; read the opinion for its findings.
Country rules
Country checks for E444
Permission depends on the market, type of food, amount and conditions. A scientific opinion or an E-number alone does not establish a legal use. These checks are separate from the stored EatMatrix rating.
Compare all eight markets and their sources
| Market | What is checked |
|---|---|
| European Union | Regulation (EC) 1333/2008, Annex II Part B, version , contains the exact code E444: Sucrose acetate isobutyrate. Listing alone does not allow every food use. Part E food categories, limits, specifications and applicable later acts still need a product-specific check. Source read: . |
| Great Britain | The FSA register record for E444 (Sucrose acetate isobutyrate) lists “Authorised” in England, Scotland and Wales. Register updated: 01 April 2025; record checked: . Food-specific conditions and specifications still need a separate legal check. |
| United States | Complete current-use review pending. Any scoped provision in the label guide above applies only to the stated use. FDA explains the applicable food-additive and GRAS framework. |
| Northern Ireland | Review pending. Check the applicable EU rules and territory arrangements; the GB register alone does not establish this status. FSA guidance is a starting source, not a verified permission for this entry. |
| Canada | Named food-use records located. Health Canada lists the preparations below for specified foods and purposes. This is conditional permission for those uses, not approval of every product or a personal safety verdict. Only the named records and conditions below were located. Exact composition and specifications still need matching. Source tables captured . List publication dates are shown separately. Good Manufacturing Practice (GMP) is a condition of use, not an unlimited amount or a recommended intake. Food and Drug Regulations B.16.003 requires the listed source, purpose, amount and other conditions to match. The official consolidation read was current to 21 September 2026; product specifications and applicable later changes still need checking. Read 1 listed food-use conditionsSucrose Acetate IsobutyrateHealth Canada: List of Permitted Food Additives with Other Purposes of Use. List published ; item S.33.
EatMatrix reading: match the exact preparation and food first. A manufacturing limit is not an acceptable daily intake (ADI). A label without the amount cannot establish exposure, and an unlisted name here does not establish a ban. |
| Australia | Review pending. Food Standards Code permissions and conditions need an additive-specific check. FSANZ food-additive rules is a starting source, not a verified permission for this entry. |
| New Zealand | Review pending. Food Standards Code permissions and conditions need an additive-specific check. FSANZ food-additive rules is a starting source, not a verified permission for this entry. |
| Japan | Review pending. The relevant list, identity and use standards need an additive-specific check. CAA food-additive lists is a starting source, not a verified permission for this entry. |
Sources & review status
Check what each source covers: an authority’s conclusion, a research finding and a country’s legal permission answer different questions.
What this guide covers
- Selected research
- 1 source summaries, with publication dates and study types. Several publications may describe the same study population.
- Official assessment sources
- Commission-listed EFSA references for E444. Bibliographic identity checked; latest findings and current use rules need separate review.
- Original ingredient record
- 2 research links; newest recorded date: . Sources added separately to this guide are not included in this count.
This guide brings together our ingredient record and the dated sources shown here. Missing information describes a gap in this guide; it does not mean an ingredient is untested, safe or harmful. This is not a complete review of every study, preparation or current country rule. The amount in a product and how it is used still matter.
How to read the ratings, research and country checksAgency labels recorded by EatMatrix
These are imported database classifications, not verified current statements from each authority. Use the dated official sources below for their actual scope and conclusions.
| Authority | Database label |
|---|---|
| FDA | Safe |
| WHO | Safe |
| EFSA | Safe |
| FSANZ | Safe |
| UK FSA | Safe |
Official assessment sources for E444
The European Commission’s re-evaluation table lists official EFSA documents for this additive. Their identifiers and subjects were checked against publisher bibliographic records. A missing research link in the EatMatrix database does not mean the additive has never been assessed.
Name in the Commission table: Sucrose acetate isobutyrate.
- Re‐evaluation of sucrose acetate isobutyrate (E 444) as a food additive
EFSA scientific opinion. Published: .
These are assessment references, including historical or group assessments. They do not establish the latest scientific conclusion, a human health benefit or risk, or current permission to use the additive in a particular food. Later assessments, corrections and food-use conditions need separate review. The recorded EatMatrix rating above is unchanged.
European Commission re-evaluation table, status as of . EatMatrix checked this bibliography on .
Database updated: . What does an E number mean on a food label?
Common questions
Frequently asked questions
What is EatMatrix's recorded rating for E444?
The recorded EatMatrix rating for E444 (Sucrose acetate isobutyrate) is “Safe”. It is calculated from labels stored in our ingredient database. These labels are not verified current regulator decisions or country permissions. A database update date is not a scientific review date.
Is E444 vegan, halal or gluten-free?
According to our ingredient data for Sucrose acetate isobutyrate — vegan: yes, vegetarian: yes, halal: yes, kosher: yes, gluten-free: yes, dairy-free: yes. Manufacturing sources can vary between products; check the label if it matters to you.
What is E444 and why is it used?
Sucrose acetate isobutyrate (SAIB) is a synthetic ester used mainly as a weighting agent in citrus-flavored soft drinks, keeping flavor oils evenly suspended so they don't float to the surface. It is also used as a glazing or coating agent in some confections. It is approved for food use within regulated limits by the FDA and EFSA.
Does E444 contain allergens?
No known allergens are recorded for Sucrose acetate isobutyrate.
Is SAIB the same as E444?
SAIB is another name for sucrose acetate isobutyrate. The FSA lists it as E444 and WHO/JECFA lists INS 444. These names help identify the ingredient on a food label.
Why is E444 used in drinks?
The US rule 21 CFR 172.833 specifies stabilising emulsions of flavouring oils in nonalcoholic beverages, subject to substance specifications and a maximum of 300 milligrams per kilogram of the finished beverage. That rule does not establish permission for every product or market.
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This page shows information and classifications recorded in our ingredient database. Current scientific and market-specific verification remains pending as described above. It is general information, not medical advice.