E460(I) · Microcrystalline Cellulose
- WHO
- Safe
- FDA
- Safe
- EFSA
- Safe
- FSANZ
- Safe
- Japan
- Safe
- UK FSA
- Safe
- Health Canada
- Safe
What is E460(I)?
Microcrystalline cellulose (MCC) is purified, partially depolymerized cellulose, typically derived from wood pulp, presented as a fine white free-flowing powder. It is used as a bulking agent, anti-caking agent, stabilizer, emulsifier, and tablet disintegrant, acting as a non-caloric filler and texturizer in reduced-fat foods, dairy products, and baked goods.
Also appears on labels as: Microcrystalline Cellulose, MCC, Cellulose, microcrystalline, Powdered cellulose, Pharmaceutical cellulose, E460(i), E 460(i), E-460(i), Food grade microcrystalline cellulose, Microcrystalline cellulose powder, Microcrystalline cellulose excipient, Inert cellulose.
What the evidence says
- Generally recognized as safe at typical food levels; high doses may cause mild gastrointestinal discomfort.
Frequently asked questions
Is E460(I) safe?
Our overall verdict for E460(I) (Microcrystalline Cellulose) is “Safe”, based on the most cautious of the major regulators’ positions — FDA: safe; WHO: safe; EFSA: safe; FSANZ: safe; Japan: safe; UK FSA: safe; Health Canada: safe.
Is E460(I) vegan, halal or gluten-free?
According to our ingredient data for Microcrystalline Cellulose — vegan: yes, vegetarian: yes, halal: yes, kosher: yes, gluten-free: yes, dairy-free: yes. Manufacturing sources can vary between products; check the label if it matters to you.
What is E460(I) and why is it used?
Microcrystalline cellulose (MCC) is purified, partially depolymerized cellulose, typically derived from wood pulp, presented as a fine white free-flowing powder. It is used as a bulking agent, anti-caking agent, stabilizer, emulsifier, and tablet disintegrant, acting as a non-caloric filler and texturizer in reduced-fat foods, dairy products, and baked goods.
Does E460(I) contain allergens?
No known allergens are recorded for Microcrystalline Cellulose, though some people report sensitivity (May cause digestive upset (bloating, gas, laxative effect) in very large quantities.).
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This page summarises publicly available regulatory assessments and research. It is general information, not medical advice. Sources: EFSA, FDA, WHO and the studies linked above.